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Faculty Directory



Daniel Szeto, Ph.D.

Associate Professor of Biology and Biochemistry

Office Phone: (951) 552-8735
Office Location: Mission Hall Room 104
Office Hours: Mon 11:00am - 1:00pmWed 11:00am - 1:00pmFri 11:00am - 1:00pm and 2:00pm - 5:00pm

Degree Major Emphasis Institution Year
Ph.D. Biomedical Sciences University of California, San Diego 1998
M.S. Molecular Biology San Diego State University 1990
B.S. Bacteriology University of California, Davis 1986

Courses Taught

Developmental Biology
Protein expression
Signaling in gene regulation


Academic Areas & Scholarly Interests

Developmental Biology
Signaling in gene regulation


Teaching Experience

Purdue University


Research, Presentations, & Publications

Jian Gao, Joseph A. Lyon, Daniel P. Szeto, and Jun Chen. (2012) In vivo imaging and quantitative analysis of zebrafish embryos by digital holographic microscopy. Biomedical Optics Express 3:2623-2635.

Jamie L. Seebald and Daniel P. Szeto. (2011) Zebrafish eve1 regulates the lateral and ventral fates of mesodermal progenitor cells at the onset of gastrulation. Dev Biol. 349:78-89

Yuling Wang, Jamie L. Seebald, Daniel P. Szeto and Joseph Irudayaraj. (2010) Biocompatibility and Biodistribution of Multiplex SERS Nanoprobes in live zebrafish Embryos. ACNano. 4:4039-4053

Ting Bai, Jamie L. Seebald, Kyu-Eui Kim, Hong-Mei Ding, Daniel P. Szeto and Henry C. Chang (2010) Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development. BMC Developmental Biology. 10:7 (Daniel P. Szeto and Henry C. Chang are co-corresponding authors)

Daniel P.Szeto and David Kimelman. (2006). The regulation of mesodermal progenitor cell commitment to somitogenesis subdivides the zebrafish body musculature into distinct domains.
Genes & Development 20:1923-1932.

David Kimelman and Daniel P. Szeto. (2006). Chordin cleavage is sizzling. Nat. Cell Biol. 8:305-307.

Mark S. Cooper, Daniel P. Szeto, Greg Sommers-Herivel, Jacek Topczewski, Lila Solnica-Krezel, Hee-Choi Kang, Iain Johnson and David Kimelman. (2005). Visualizing Morphogenesis in Transgenic Zebrafish Embryos using BODIPY TR, Methyl Ester As a Vital Counterstain for GFP. Developmental Dynamics 232: 359-368.

Daniel P. Szeto and David Kimelman. (2004). Combinatorial Gene Regulation by Bmp and Wnt in Zebrafish Posterior Mesoderm formation. Development 131:3751-3760.

Daniel P. Szeto, Kevin J. P. Griffin and David Kimelman. (2002). hrT is required for cardiovascular development in zebrafish. Development 129: 5093-5101.

Mathias Treier, Shawn O’Connell, Anatoli Gleiberman, Jenny Price, Daniel Szeto, Rob Burgess, Pao-Tien Chuang, Andrew P. McMahon, and Michael G. Rosenfeld. (2001). Hedgehog signaling is required
for pituitary gland development. Development 128: 377-388.

Zhiyong Wang, David W. Rose, Ola Hermanson, Forrest Liu, Thomas Herman, Wei Wu, Daniel Szeto, Anatoli Gleiberman, Anna Krones, Katherine Pratt, Ron Rosenfeld, Christopher K. Glass, and Michael G. Rosenfeld. (2000). Regulation of somatic growth by the p160 coactivator p/cip. Proc. Natl. Acad. Sci. USA. 97:13549-13554.

Rosenfeld, M.G., Briata P., Dasen, J., Gleiberman, A. S. Kioussi, C., Lin, C., O’Connell, S. M., Ryan, A., Szeto, D. P., and Treier, M. (2000). Multistep signaling and transcriptional requirements for pituitary
organogenesis in vivo. Recent Prog Horm Res. 55:1-13.

Chijen R. Lin, Chrissa Kloussi, Shawn O’Connell, Paola Briata, Daniel Szeto, Forrest Liu, Juan Carlo Izpisúa-Belmonte, and Michael G. Rosenfeld. (1999). Pitx2 regulates lung asymmetry, cardiac positioning and
pituitary and tooth morphogenesis. Nature 401: 279-282.

Jeremy S. Dasen, Shawn M. O’Connell, Sarah E. Flynn, Mathias Treier, Anatoli S. Gleiberman, Daniel P. Szeto, Farideh Hooshmand, Aneel K. Aggarwal, and Michael G. Rosenfeld. (1999). Reciprocal Interactions of Pit1 and GATA2 Mediate Signaling Gradient-Induced Determination of Pituitary Cell Types. Cell 97: 587-698.

Daniel P. Szeto, Concepion Rodriguez-Esteban, Aimee K. Ryan, Shawn M. O’Connell, Forrest Liu, Chrissa Kioussi, Anatoli S. Gleiberman, Juan Carlo Izpisúa-Belmonte, and Michael G. Rosenfeld. (1999). Role of the Bicoid-related homeodomain Factor Pitx1 in specifying hindlimb Morphogenesis and pituitary development. Genes & Development 13: 484-494.

Lan Xu, Robert M. Lavinsky, Jeremy S. Dasen, Sarah E. Flynn, Eileen M. McInerney, Tina-Marie Mullen, Thorsten Heinzel, Daniel Szeto, Edward Korzus, Riki Kurokawa, Aneel K. Aggarwal, David W. Rose, Christopher K. Glass, and Michael G. Rosenfeld. (1998). Distinct Histone Acetyltransferases and CBP Domain Requirements for activation of
Pit-1 by Different Signalling Pathways. Nature 395: 301-306.

Mathias Treier, Anatoli S. Gleiberman, Shawn M. O'Connell, Daniel P. Szeto, Jill A. McMahon, Andrew P. McMahon, and Michael G. Rosenfeld. (1998). Multistep Signaling Requirement for Pituitary Organogenesis In Vivo. Genes & Development 12: 1691-1704.

Jon H. Miyake, Daniel P. Szeto, and William E. Stumph. (1997). Analysis of the Structure and expression of the chicken gene encoding a homolog of the human RREB-1 transcription factor. Gene 202: 177-186.

Daniel P. Szeto, Aimee K. Ryan, Shawn M. O'Connell, and Michael G. Rosenfeld. (1996). P-OTX: A PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development. Proc. Natl. Acad. Sci. USA 93: 7706-7710.

Jeffrey M. Holloway, Daniel P. Szeto, Kathleen M. Scully, Christopher Glass, and Michael G. Rosenfeld. (1995). Pit-1 Binding to Specific DNA Sites as a Monomer or Dimer Determines Gene-specific Use of a Tyrosine-Dependent Synergy Domain. Genes & Development 9: 1992-2006. (co-first authorship)

Kenneth A. Roebuck, Daniel P. Szeto, Kenneth P. Green, Qian N. Fan, and William E. Stumph. (1990). Octamer and SPH Motifs in the U1 Enhancer Cooperate to Activate U1 RNA Gene Expression. Molecular and Cellular Biology 10: 341-352.

Popham, D. L., Szeto, D., Keener, J., and Kustu, S. (1989). Function of a Bacterial Activator Protein that binds to Transcriptional Enhancers. Science 243: 629-635.


Church Membership & Activities

Member of the Grove Community Church

Mentor of Rainbow Chinese Christian Fellowship


Personal Philosophy

Whatever you do, work at it with all your heart, as working for the Lord, not for men (Colossians 3:23)