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Hyun-Woo Park, Ph.D.

Professor of Biology

Office Phone: (951) 343-4766
E-mail: hpark@calbaptist.edu
Office Location: James Building, 201
Office Hours: MW 8-10 am & 11-12 pm; F 8-10 am

Degree Major Emphasis Institution Year
Ph.D. Entomology/Insect Pathology University of California, Riverside 1999
M.S. Agricultural Sciences/Insect Pathology Seoul National University, Korea 1995
B.S. Agricultural Sciences Seoul National University, Korea 1990

Courses Taught

BIO114 General Botany with Lab
BIO143 Principles of Biology
BIO143L Principles of Biology Lab
BIO205 Human Microbiology with Lab
BIO305 Microbiology with Lab
BIO380 Biology Seminar
BIO490 Senior Research in Biology
HSC491 Internship in Health Science

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Academic Areas & Scholarly Interests

Molecular genetics of insect-pathogenic bacteria, Bacillus thuringiensis and Bacillus sphaericus

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Teaching Experience

Graduate-level Insect Molecular Genetics and Insect Pathology at Florida A&M University
Graduate-level Microbial Genetics at the University of California, Riverside
Undergraduate-level Forensic Entomology at Florida A&M University

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Research, Presentations, & Publications

REVIEWED: SCIENTIFIC JOURNAL PUBLICATIONS

Park, H.-W., H.-S. Kim, D.-W. Lee, Y.-M. Yu, B.-R. Jin and S.-K. Kang. 1995. Expression and synergistic effect of three types of crystal protein genes in Bacillus thuringiensis. Biochemical and Biophysical Research Communications 214, 602-607.

Roh, J.-Y., H.-W. Park, B.-R. Jin, H.-S. Kim, Y.-M. Yu and S.-K. Kang. 1996. Characterization of novel non-toxic Bacillus thuringiensis isolates from Korea. Letters in Applied Microbiology 23, 249-252.

Roh, J.-Y., H.-W. Park, Y.-H. Je, D.-W. Lee, B.-R. Jin, H.-W. Oh, S. S. Gill and S.-K. Kang. 1997. Expression of mosquitocidal crystal protein genes in noninsecticidal Bacillus thuringiensis subsp. israelensis. Letters in Applied Microbiology 24, 451-454.

Chang, J.-H., J.-Y. Roh, Y.-H. Je, H.-W. Park, B.-R. Jin, S.-D. Woo and S.-K. Kang. 1998. Isolation of a strain of Bacillus thuringiensis ssp. kurstaki HD-1 encoding δ-endotoxin Cry1E. Letters in Applied Microbiology 26, 387-390.

Park, H.-W., J.-Y. Roh, Y.-H. Je, B.-R. Jin, H.-W. Oh, H.-Y. Park and S.-K. Kang. 1998. Isolation of non-insecticidal Bacillus thuringiensis strain belonging to serotype H8a8b. Letters in Applied Microbiology 27, 62-66.

Park, H.-W., B. Ge, L. S. Bauer and B. A. Federici. 1998. Optimization of Cry3A yields in Bacillus thuringiensis by use of sporulation-dependent promoters in combination with the STAB-SD mRNA sequence. Applied and Environmental Microbiology 64, 3932-3938.

Chang, J.-H., Y.-H. Je, J.-Y. Roh, H.-W. Park, B.-R. Jin, D.-W. Lee, S.-H. Kim, Z.-W. Yang and S.-K. Kang. 1999. Isolation and characterization of a strain of Bacillus thuringiensis serovar kenyae encoding only delta-endotoxin Cry1E. Applied Entomology and Zoology 34, 379-382.

Park, H.-W., D. K. Bideshi, J. J. Johnson and B. A. Federici. 1999. Differential enhancement of Cry2A versus Cry11A yields in Bacillus thuringiensis by use of the cry3A STAB mRNA sequence. FEMS Microbiology Letters 181, 319-327.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2000. Molecular genetic manipulation of truncated Cry1C protein synthesis in Bacillus thuringiensis to improve stability and yield. Applied and Environmental Microbiology 66, 4449-4455.

Park, H.-W. and B. A. Federici. 2000. Domain I plays an important role in the crystallization of Cry3A in Bacillus thuringiensis. Molecular Biotechnology 16, 97-107.

Park, H.-W., A. Delécluse and B. A. Federici. 2001. Construction and characterization of a recombinant Bacillus thuringiensis subsp. israelensis strain that produces Cry11B. Journal of Invertebrate Pathology 78, 37-44.

Je, Y.-H., B.-R. Jin, H.-W. Park, J.-Y. Roh, J.-H. Chang, S.-J. Seo, J. A. Olszewski, D. R. O’Reilly and S.-K. Kang. 2003. Baculovirus expression vectors that incorporate the foreign protein into viral occlusion bodies. BioTechniques 34, 81-87.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2003. Recombinant strain of Bacillus thuringiensis producing Cyt1A, Cry11B and the Bacillus sphaericus binary toxin. Applied and Environmental Microbiology 69, 1331-1334.

Park, H.-W. and B. A. Federici. 2004. Effect of specific mutations in helix alpha-7 of Domain I on the stability and crystallization of Cry3A in Bacillus thuringiensis. Molecular Biotechnology 27, 89-100.

Wirth, M. C., H.-W. Park, W. E. Walton and B. A. Federici. 2005. Cyt1A of Bacillus thuringiensis delays evolution of resistance to Cry11A in the mosquito, Culex quinquefasciatus. Applied and Environmental Microbiology 71, 185-189.

Hughes, P. A., M. M. Stevens, H.-W. Park, B. A. Federici, E. S. Dennis and R. Akhurst. 2005. Response of larval Chironomus tepperi (Diptera: Chironomidae) to individual Bacillus thuringiensis var. israelensis toxins and toxin mixtures. Journal of Invertebrate Pathology 88, 34-39.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2005. Synthesis of additional endotoxins in Bacillus thuringiensis subsp. morrisoni PG-14 and Bacillus thuringiensis subsp. jegathesan significantly improves their mosquitocidal efficacy. Journal of Medical Entomology 42, 337-341.

Park, H.-W., D. K. Bideshi, M. C. Wirth, J. J. Johnson, W. E. Walton and B. A. Federici. 2005. Recombinant larvicidal bacteria with markedly improved efficacy against Culex vectors of West Nile Virus. The American Journal of Tropical Medicine and Hygiene 72, 732-738.

Tang, M., D. K. Bideshi, H.-W. Park and B. A. Federici. 2006. A mini-replicon from pBtoxis of Bacillus thuringiensis subsp. israelensis. Applied and Environmental Microbiology 72, 6948-6954.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2007. The 20-kDa protein of Bacillus thuringiensis subsp. israelensis enhances Bacillus sphaericus 2362 Bin toxin synthesis. Current Microbiology 55, 119-124.

Tang, M., D. K. Bideshi, H.-W. Park and B. A. Federici. 2007. Iteron-binding ORF157 and FtsZ-like ORF156 proteins encoded by pBtoxis play a role in its replication in Bacillus thuringiensis subsp. israelensis. Journal of Bacteriology 189, 8053-8058.

Park, H.-W., C. M. Mangum, H. Zhong and S. R. Hayes. 2007. Isolation of Bacillus sphaericus with improved efficacy against Culex quinquefasciatus. Journal of the American Mosquito Control Association 23, 478-480.

Park, H.-W., S. R. Hayes and C. M. Mangum. 2008. Distribution of mosquitocidal Bacillus thuringiensis and Bacillus sphaericus from sediment samples in Florida. Journal of Asia-Pacific Entomology 11, 217-220.

Park, H.-W., S. R. Hayes, G. M. Stout, G. Day-Hall, M. D. Latham and J. P. Hunter. 2009. Identification of two mosquitocidal Bacillus cereus strains showing different host ranges. Journal of Invertebrate Pathology 100, 54-56.

Park, H.-W., M. Tang, Y. Sakano and B. A. Federici. 2009. A 1.1-kilobase region downstream of the bin operon in Bacillus sphaericus strain 2362 decreases Bin yield and crystal size in strain 2297. Applied and Environmental Microbiology 75, 878-881.

Hayes, S. R., M. Hudon and H.-W. Park. 2011. Isolation of novel Bacillus species showing high mosquitocidal activity against several mosquito species. Journal of Invertebrate Pathology 107, 79-81.

Park, H.-W., J. A. Devera, B. A. Prins and D. K. Bideshi. 2011. The dual-activity insecticidal protein, Cry2Aa, does not enhance the mosquitocidal activity of Bacillus thuringiensis subsp. israelensis. Journal of Asia-Pacific Entomology 14, 429-431.

Barboza-Corona, J. E., H.-W. Park, D. K. Bideshi and B. A. Federici. 2012. The 60-kDa protein encoded by orf2 in the cry19A operon of Bacillus thuringiensis subsp. jegathesan functions as a C-terminal crystallization domain. Applied and Environmental Microbiology 78, 2005-2012.

Park, H.-W., B. C. Pino, S. Kozervanich-Chong, E. A. Hafkenscheid, R. M. Oliverio, B. A. Federici and D. K. Bideshi. 2013. Cyt1Aa from Bacillus thuringiensis subsp. israelensis enhances mosquitocidal activity of B. thuringiensis subsp. kurstaki HD-1 against Aedes aegypti but not Culex quinquefasciatus. Journal of Microbiology and Biotechnology 23, 88-91.

Sun, Y., Q. Zhao, L. Xia, X. Ding, Q. Hu, B. A. Federici and H.-W. Park. 2013. Identification and characterization of three previously undescribed crystal proteins from Bacillus thuringiensis subsp. jegathesan. Applied and Environmental Microbiology 79, 3364-3370.

Bideshi, D. K., G. Waldrop, M. T. Fernandez-Luna, M. Diaz-Mendoza, M. C. Wirth, J. J. Johnson, H.-W. Park and B. A. Federici. 2013. Intermolecular interaction between Cry2Aa and Cyt1Aa and its effect on larvicidal activity against Culex quinquefasciatus. Journal of Microbiology and Biotechnology 23, 1107-1115.

Sun, Y., Q. Zhao, D. Zheng, X. Ding, J. Wang, Q. Hu, Z. Yuan, H.-W. Park and L. Xia. 2014. Construction and characterization of the interdomain chimeras using Cry11Aa and Cry11Ba from Bacillus thuringiensis and identification of a possible novel toxic chimera. Biotechnology Letters 36, 105-111.

INVITED CHAPTERS AND REVIEW ARTICLES:

Federici, B. A., H.-W. Park, D. K. Bideshi and B. Ge. 2000. Chapter 7.2 Genetic engineering of bacterial insecticides for improved efficacy against medically important diptera. In “Entomopathogenic Bacteria: from Laboratory to Field Application.” (J. F. Charles, A. Delécluse and C. Niesen-LeRoux eds.), pp. 461-484. Kluwer Academic Publishers, Amsterdam.

Park, H.-W. and B. A. Federici. 2000. Genetic factors affecting insecticidal crystal protein synthesis in Bacillus thuringiensis. International Journal of Industrial Entomology 1, 1-7.

Federici, B. A., H.-W. Park, D. K. Bideshi, M. C. Wirth and J. J. Johnson. 2003. Recombinant bacteria for mosquito control. Journal of Experimental Biology 206, 3877-3885.

Federici, B. A., H.-W. Park and Y. Sakano. 2006. Insecticidal protein crystals of Bacillus thuringiensis. In Microbiology Monographs, Volume 1, “Inclusions in Prokaryotes” (J. M. Shively ed.), pp. 195-236. Springer-Verlag, Heidelberg.

Park, H.-W., B. A. Federici and Y. Sakano. 2006. Inclusion proteins from other insecticidal bacteria. In Microbiology Monographs, Volume 1, “Inclusions in Prokaryotes” (J. M. Shively ed.), pp. 321-330. Springer-Verlag, Heidelberg.

Federici, B. A., H.-W. Park, D. K. Bideshi, M. C. Wirth, J. J. Johnson, Y. Sakano and M. Tang. 2007. Developing recombinant bacteria for control of mosquito larvae. In “Biorational Control of Mosquitoes.” (T. G. Floore ed.), pp. 164-175. American Mosquito Control Association, Mount Laurel.

Park, H.-W. 2008. Current status of larvicidal bacteria for mosquito control: A review. Technical Bulletin of the Florida Mosquito Control Association 8, 31-35.

Park, H.-W. and B. A. Federici. 2009. Chapter 12. Genetic engineering of bacteria to improve efficacy using the insecticidal proteins of Bacillus species. In “Insect Pathogens – Molecular Approaches and Techniques.” (S. P. Stock, J. Vandenberg, I. Glazer and N. Boemare eds.), pp. 275-305. CABI Publishing, Cambridge.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2010. Properties and applied use of the mosquitocidal bacterium, Bacillus sphaericus. Journal of Asia-Pacific Entomology 13, 159-168.

Federici, B. A., H.-W. Park and D. K. Bideshi. 2010. Overview of the Basic biology of Bacillus thuringiensis with emphasis on genetic engineering of bacterial larvicides for mosquito control. In “Entomopathogenic Bacterial Toxins as Biological Control Agents.” (A. Zaritsky and E. Ben-Dov eds.). Supplementary Issue, The Open Toxinology Journal 3, 154-171.

PROCEEDINGS OF SYMPOSIA OR TECHNICAL MEETINGS:

Federici, B. A., H.-W. Park and D. K. Bideshi. 2001. Improving the efficacy of Bacillus thuringiensis insecticides: From molecular biology to practical applications. In “Proceedings of the Centennial Symposium Commemorating Ishiwata's Discovery of Bacillus thuringiensis.” (M. Ohba, O. Nakamura, E. Mizuki and T. Akao eds.), pp. 15-20. Kurume, Japan.

Federici, B. A., H.-W. Park, D. K. Bideshi, J. J. Johnson and M. C. Wirth. 2001. Synergistic interactions that enhance the pathogenicity of Bacillus thuringiensis. In “Proceedings of the 4th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact.” pp. 25-31. Canberra, Australia.

Park, H.-W. 2007. Molecular genetic strategies to enhance efficacy of entomopathogenic bacteria. In “Proceedings of the Korea Conference on Innovative Science and Technology 2007. Molecular Host – Parasite Interactions: New Horizon on Interface Biology.” pp. 159-168. Jeju, Korea.

Park, H.-W., S. R. Hayes and C. M. Mangum. 2007. Biological control of mosquitoes: Microbiology, molecular genetics and biophysics. In “Proceedings of the CESTA 2007 Research Forum.” pp. 37-38. Florida A & M University, Tallahassee, Florida.

Park, H.-W. 2008. Entomopathogenic bacteria for vector control: Molecular genetic exploration and novel toxin discovery. In “Proceedings of the 1st China – Korea Joint Symposium on Insect Biotechnology.” p. 23. Wuhan, China.

Park, H.-W. 2009. Discovery of novel mosquitocidal bacteria from mosquito larval habitats. In “Proceedings of the 1st International Symposium on Insect Biotechnology & 2nd Korea – China Joint Symposium on Insect Biotechnology.” p. 26. Busan, Korea.

PATENTS:

Kang, S.-K., H.-S. Kim, H.-W. Park, B.-R. Jin, S.-D. Woo, Y.-H. Je, D.-W. Lee, J.-Y. Roh, J.-H. Chang and Y.-M. Yu. 1998. Insecticidal protein of Bacillus thuringiensis NT0423 and microbial insecticide using it. Korea Patent No. 98-3455.

Kang, S.-K., Y.-H. Je, B.-R. Jin, H.-W. Park, J.-Y. Roh and J.-H. Chang. 1998. Recombinant baculovirus, process for preparing thereof and microbial insecticide containing it. Korea Patent No. 98-11914.

Kang, S.-K., Y.-H. Je, B.-R. Jin, H.-W. Park, J.-Y. Roh and J.-H. Chang. 1998. Recombinant baculovirus, construction method thereof and insect pesticidal composition containing the same. U.S. Patent No. 6,338,846.

Federici, B. A., D. K. Bideshi, H.-W. Park and M. C. Wirth. 2004. Insecticidal bacteria, and methods for making and using them. U.S. Patent No. 6,720,167.

Park, H.-W., C. M. Mangum and H. Zhong. 2007. A novel mosquitocidal bacterium and its toxin. U.S. Patent Application No. 11/770,203.

Park, H.-W., S. R. Hayes, G. M. Stout and M. D. Latham. 2008. A novel Bacillus cereus mosquitocidal bacterium mainly active against Ochlerotatus taeniorhynchus and its toxin. U.S. Patent Application No. 122,838.

Park, H.-W., S. R. Hayes, G. Day Hall and J. P. Hunter. 2008. A novel Bacillus cereus mosquitocidal bacterium mainly active against Culex quinquefasciatus and its toxin. U.S. Patent Application No. 122,839.

Park, H.-W., S. R. Hayes and M. Hudon. 2010. New strain of highly mosquitocidal Bacillus. U.S. Patent Application No. 12/754,259.

Park, H.-W., S. R. Hayes and M. Hudon. 2010. New strain of highly mosquitocidal Bacillus. U.S. Patent Application No. 12/754,322.

CONTRIBUTED PAPER PRESENTATIONS:

Park, H.-W., B. Ge, L. S. Bauer and B. A. Federici. 1998. Very high levels of Cry3A synthesis are obtained in Bacillus thuringiensis using dual sporulation-dependent promoters in combination with the STAB-SD mRNA sequence. 31st Annual Meeting of the Society for Invertebrate Pathology, VIIth International Colloquium on Invertebrate Pathology and Microbial Control, and IVth International Conference on Bacillus thuringiensis. Sapporo, Japan.

Roh, J.-Y., H.-W. Park, Y.-H. Je, J.-H. Chang, B.-R. Jin and S.-K. Kang. 1998. Isolation of a noninsecticidal Bacillus thuringiensis strain belonging to subsp. morrisoni (H8a8b). 31st Annual Meeting of the Society for Invertebrate Pathology, VIIth International Colloquium on Invertebrate Pathology and Microbial Control, and IVth International Conference on Bacillus thuringiensis. Sapporo, Japan.

Chang, J.-H., J.-Y. Roh, Y.-H. Je, H.-W. Park, B.-R. Jin, Z.-W. Yang and S.-K. Kang. 1998. Isolation of Spodoptera-specific Bacillus thuringiensis strains in Korea. 2nd International Symposium on Biopesticides. Wuhan, China.

Ge, B., H.-W. Park and B. A. Federici. 1998. Regulation of crystal protein synthesis and crystallization in Bacillus thuringiensis. 2nd International Symposium on Biopesticides. Wuhan, China.

Park, H.-W. and B. A. Federici. 1999. Domain I plays a key role in Cry3A crystallization. 32nd Annual Meeting of the Society for Invertebrate Pathology. Irvine, California.

Park, H.-W. and B. A. Federici. 2000. Structural role for Domain I helix alpha-7 in Cry3A crystallization in vivo in Bacillus thuringiensis. 33rd Annual Meeting of the Society for Invertebrate Pathology and Vth International Conference on Bacillus thuringiensis. Guanajuato, Mexico.

Federici, B. A., M. C. Wirth, D. K. Bideshi, H.-W. Park and W. E. Walton. 2000. Role of Cyt1A in managing resistance to mosquitocidal proteins of Bacillus thuringiensis and Bacillus sphaericus. 33rd Annual Meeting of the Society for Invertebrate Pathology and Vth International Conference on Bacillus thuringiensis. Guanajuato, Mexico.

Park, H.-W., A. Delecluse and B. A. Federici. 2000. Properties of a recombinant Bacillus thuringiensis subsp. israelensis IPS-82 that produces Cry11B. 33rd Annual Meeting of the Society for Invertebrate Pathology and Vth International Conference on Bacillus thuringiensis. Guanajuato, Mexico.

Federici, B. A., D. K. Bideshi, H.-W. Park, M. C. Wirth, W. E. Walton and J. J. Johnson. 2000. Markedly improved bacterial insecticides for vectors by combining Bti and Bs proteins. 33rd Annual Meeting of the Society for Invertebrate Pathology and Vth International Conference on Bacillus thuringiensis. Guanajuato, Mexico.

Federici, B. A., D. K. Bideshi, H.-W. Park, M. C. Wirth, W. E. Walton and J. J. Johnson. 2001. Genetically engineered bacteria containing Bti and Bs proteins for improved control of nuisance and vector mosquito larvae. 69th Annual Conference of the Mosquito and Vector Control Association of California. Napa, California.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2001. Construction and characterization of a Bacillus thuringiensis strain producing Cry11B, Cyt1A and Bacillus sphaericus 2362 binary toxin. 34th Annual Meeting of the Society for Invertebrate Pathology. Noordwijkerhout, The Netherlands.

Federici, B. A., D. K. Bideshi, H.-W. Park, M. C. Wirth, W. E. Walton and J. J. Johnson. 2001. Markedly improved recombinant Bacillus thuringiensis subsp. israelensis that synthesizes a high level of the Bacillus sphaericus binary toxin. 34th Annual Meeting of the Society for Invertebrate Pathology. Noordwijkerhout, The Netherlands.

Federici, B. A., H.-W. Park, D. K. Bideshi, J. J. Johnson, M. C. Wirth and W. E. Walton. 2001. New recombinant bacterial larvicides for mosquito control. 2001 Entomological Society of America Annual Meeting. San Diego, California.

Federici, B. A., H.-W. Park, D. K. Bideshi, J. J. Johnson, M. C. Wirth and W. E. Walton. 2002. New recombinant bacteria for mosquito control. 70th Annual Conference of the Mosquito and Vector Control Association of California. Fish Camp, California.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2002. Addition of the Bacillus sphaericus binary toxin to Bacillus thuringiensis subsp. morrisoni (PG-14) and Bacillus thuringiensis subsp. jegathesan markedly improves their toxicity. 35th Annual Meeting of the Society for Invertebrate Pathology, VIIIth International Colloquium on Invertebrate Pathology and Microbial Control, and VIth International Conference on Bacillus thuringiensis. Fos do Iguassu, Brazil.

Park, H.-W., B. A. Federici, D. K. Bideshi, M. C. Wirth and W. E. Walton. 2003. Recent progress on recombinant larvicidal bacteria for mosquito control. 71st Annual Conference of the Mosquito and Vector Control Association of California. Palm Springs, California.

Barboza-Corona, J. E., H.-W. Park and B. A. Federici. 2003. Molecular genetic analysis and enhancement of Cry19A synthesis in Bacillus thuringiensis. 36th Annual Meeting of the Society for Invertebrate Pathology. Burlington, Vermont.

Federici, B. A., M. C. Wirth, J. J. Johnson, H.-W. Park, D. K. Bideshi and W. E. Walton. 2003. Cyt1A synergizes toxicity of Bs Bin by enhancing its insertion through the mosquito midgut microvillar membrane. 36th Annual Meeting of the Society for Invertebrate Pathology. Burlington, Vermont.

Park, H.-W., D. K. Bideshi and B. A. Federici. 2004. The 20-kDa protein of Bacillus thuringiensis subsp. israelensis enhances B. sphaericus 2362 Bin toxin production. 37th Annual Meeting of the Society for Invertebrate Pathology and VIIth International Conference on Bacillus thuringiensis. Helsinki, Finland.

Sakano, Y., H.-W. Park, B. Ge and B. A. Federici. 2004. High level of Cyt1A synthesis in Bacillus thuringiensis subsp. israelensis is due to three promoters and a strong 3’ mRNA stem-loop structure. 37th Annual Meeting of the Society for Invertebrate Pathology and VIIth International Conference on Bacillus thuringiensis. Helsinki, Finland.

Sakano, Y., H.-W. Park and B. A. Federici. 2005. Individual characterization of the three cyt1A promoters of Bacillus thuringiensis subsp. israelensis. 38th Annual Meeting of the Society for Invertebrate Pathology. Anchorage, Alaska.

Park, H.-W., Y. Sakano and B. A. Federici. 2006. A 1.1 kb fragment downstream from the bin operon in Bacillus sphaericus 2362 affects Bin yield and crystal size. 39th Annual Meeting of the Society for Invertebrate Pathology, IXth International Colloquium on Invertebrate Pathology and Microbial Control, and XIIIth International Conference on Bacillus thuringiensis. Wuhan, China.

Sakano, Y., H.-W. Park and B. A. Federici. 2006. Effects of Cyt1A yield reduction on Bacillus sphaericus Bin toxin synthesis in recombinant Bacillus thuringiensis. 39th Annual Meeting of the Society for Invertebrate Pathology, IXth International Colloquium on Invertebrate Pathology and Microbial Control, and XIIIth International Conference on Bacillus thuringiensis. Wuhan, China.

Tang, M., D. K. Bideshi, H.-W. Park and B. A. Federici. 2006. A mini-replicon from pBtoxis of Bacillus thuringiensis subsp. israelensis. 39th Annual Meeting of the Society for Invertebrate Pathology, IXth International Colloquium on Invertebrate Pathology and Microbial Control, and XIIIth International Conference on Bacillus thuringiensis. Wuhan, China.

Park, H.-W., C. M. Mangum, H. Zhong and S. R. Hayes. 2007. Characterization of mosquitocidal and non-mosquitocidal Bacillus sphaericus isolates. 40th Annual Meeting of the Society for Invertebrate Pathology and 1st International Forum on Entomopathogenic Nematodes and Symbiotic Bacteria. Quebec City, Canada.

Tang, M., D. K. Bideshi, H.-W. Park and B. A. Federici. 2007. Interactions between ORF157, ORF156 and the iteron in replication of pBtoxis of Bacillus thuringiensis subsp. israelensis. 40th Annual Meeting of the Society for Invertebrate Pathology and 1st International Forum on Entomopathogenic Nematodes and Symbiotic Bacteria. Quebec City, Canada.

Hayes, S. R., H.-W. Park, G. Stout, M. Latham, G. Day and J. Hunter. 2007. Isolation of bacteria producing novel mosquitocidal toxins. 79th Annual Meeting of the Florida Mosquito Control Association. Jacksonville, Florida.

Nevels, K., H.-W. Park, W. Pathaichindachote, B. Promdonkoy and P. Butko. 2008. Site-directed mutagenesis of the Bt toxin Cyt1A for intramolecular distance determination by FRET. 52nd Annual Meeting of the Biophysical Society and 16th IUPAB International Biophysics Congress. Long Beach, California.

Park, H.-W. and S. R. Hayes. 2008. Characterization of mosquitocidal Bacillus cereus toxic to Ochlerotatus taeniorhynchus and Culex quinquefasciatus. 41st Annual Meeting of the Society for Invertebrate Pathology and 9th International Conference on Bacillus thuringiensis. Coventry, United Kingdom.

Hayes, S. R. and H.-W. Park. 2008. Construction and characterization of recombinant mosquitocidal Cry and Bin toxins to improve efficacy. 1st China – Korea Joint Symposium on Insect Biotechnology. Wuhan, China.

Saleem, F., M. Akhtar, A. R. Shakoori and H.-W. Park. 2008. Characterization of the Cry2Ac7 toxin from a Pakistani isolate of Bacillus thuringiensis (SBS BT-1). 1st China – Korea Joint Symposium on Insect Biotechnology. Wuhan, China.

Saleem, F., H.-W. Park, M. Akhtar and A. R. Shakoori. 2008. Molecular genetic analysis of the cry2Ac11 operon from the HD29 strain of Bacillus thuringiensis subsp. galleriae. 1st China – Korea Joint Symposium on Insect Biotechnology. Wuhan, China.

Hayes, S. R. and H.-W. Park. 2008. Construction and characterization of the chimeric-scanning mutant toxins from Bacillus thuringiensis and Bacillus sphaericus. 2nd Annual Joint Graduate Feeder Conference and Student Research Forum. Florida A & M University, Tallahassee, Florida.

Hayes, S. R. and H.-W. Park. 2008. Chimeric mosquitocidal toxin production for enhancing their efficacy. 80th Annual Meeting of the Florida Mosquito Control Association. Panama City Beach, Florida.

Sun, Y. and H.-W. Park. 2009. Direct analysis of the crystal and spore mixture from six Bacillus thuringiensis strains by a non-electrophoretic in-gel tryptic digestion coupled with mass spectrometry. 1st International Symposium on Insect Biotechnology and 2nd Korea – China Joint Symposium on Insect Biotechnology. Busan, Korea.

Hayes, S. R. and H.-W. Park. 2009. Mosquitocidal activities of Bacillus cereus strains M413 and C32. 1st International Symposium on Insect Biotechnology and 2nd Korea – China Joint Symposium on Insect Biotechnology. Busan, Korea.

Saleem, F., H.-W. Park, M. Akhtar and A. R. Shakoori. 2009. Modification of the nucleotides between RBS and ATG resulted in dramatic increase of Cry2Ac synthesis. 21st IUBMB & 12th FAOBMB International Congress of Biochemistry and Molecular Biology. Shanghai, China.

Hayes, S. R., M. Hudon and H.-W. Park. 2009. Identification and characterization of Bacillus species toxic to several mosquito species. 42nd Annual Meeting of the Society for Invertebrate Pathology. Park City, Utah.

Sun, Y. and H.-W. Park. 2009. Proteomic analysis of the crystal and spore mixture from six Bacillus thuringiensis strains to search for novel mosquitocidal proteins. 42nd Annual Meeting of the Society for Invertebrate Pathology. Park City, Utah.

Saleem, F., H.-W. Park, M. Akhtar and A. R. Shakoori. 2009. Overproduction of Cry2Ac by modification of nucleotide sequences between ribosome-binding site and start codon in Bacillus thuringiensis. 42nd Annual Meeting of the Society for Invertebrate Pathology. Park City, Utah.

Wang, Y., P. Kukutla, S. R. Hayes, H.-W. Park and J. Xu. 2009. Anopheles gambiae larval antimicrobial responses upon exposure to a sublethal dose of Bacillus sphaericus. 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene. Washington, D.C.

Hayes, S. R. and H.-W. Park. 2010. Novel mosquitocidal Bacillus species toxic to several mosquito species. 1st Annual CESTA Dean’s Research Forum. Florida A & M University, Tallahassee, Florida.

Bideshi, D. K., G. Waldrop, M. C. Wirth, J. J. Johnson, M. Diaz-Mendoza, H.-W. Park and B. A. Federici. 2010. Cyt1Aa Synergizes the Larvicidal Activity of Cry2Aa against Culex quinquefasciatus through direct intermolecular interaction. 43th Annual Meeting of the Society for Invertebrate Pathology, 10th International Colloquium on Invertebrate Pathology and Microbial Control, and The Final Meeting of COST862: Bacterial Toxins for Insect Control. Trabzon, Turkey.

Saleem, F., H.-W. Park, M. Akhtar and A. R. Shakoori. 2010. Modification of nucleotide sequences between RBS and start codon in Bacillus thuringiensis resulted in increased level of cry2Ac mRNA. 43th Annual Meeting of the Society for Invertebrate Pathology, 10th International Colloquium on Invertebrate Pathology and Microbial Control, and The Final Meeting of COST862: Bacterial Toxins for Insect Control. Trabzon, Turkey.

Zhong, H., H.-W. Park, S. Hayes and T. Ouimet. 2011. Efficacy of novel mosquitocidal Bacillus sp. isolates and their impact on mosquitofish. 77th Annual Meeting of the American Mosquito Control Association. Anaheim, California.

Zhong, H., H.-W. Park, S. Hayes and T. Ouimet. 2011. The efficacy and impact of two novel Bacillus sp. islates. 2nd International Forum for Mosquito Control. Beijing, China.

Barboza-Corona, J. E., H.-W. Park, D. K. Bideshi and B. A. Federici. 2011. The 60-kDa protein encoded by orf2 in the cry19A operon of Bacillus thuringiensis subsp. jegathesan functions as a C-terminus of the 135-kDa Class Cry proteins. 2011 International Congress on Invertebrate Pathology & Microbial Control, OECD Symposium on Disease in Aquatic Crustaceans and 44th Annual Meeting of the Society for Invertebrate Pathology. Halifax, Canada.

Federici, B. A., M. C. Wirth, J. J. Johnson, H.-W. Park, D. K. Bideshi and W. E. Walton. 2011. Cyt1A of Bacillus thuringiensis restores Bacillus sphaericus Bin toxicity via large microvillar lesions, not cation channels, in Bin-resistant larvae of Culex quinquefasciatus. 2011 International Congress on Invertebrate Pathology & Microbial Control, OECD Symposium on Disease in Aquatic Crustaceans and 44th Annual Meeting of the Society for Invertebrate Pathology. Halifax, Canada.

Oliverio, R. M. and H.-W. Park. 2012. Identification and characterization of the novel bipyramidal crystal protein gene in Bacillus thuringiensis subsp. morrisoni PG-14. 37th Annual West Coast Biological Sciences Undergraduate Research Conference. Los Angeles, California.

Park, H.-W., J. A. Devera, B. A. Prins, R. Maynard and D. K. Bideshi. 2012. The dual-activity insecticidal protein, Cry2Aa, does not enhance the mosquitocidal activity of Bacillus thuringiensis subsp. israelensis. 67th Annual Meeting of the American Scientific Affiliation. San Diego, California.

Sun, Y., L. Xia, Q. Zhao, B. A. Federici and H.-W. Park. 2012. Identification of three new Cry proteins synthesized by Bacillus thuringiensis subsp. jegathesan. Insect Pathology Symposium, XXIV International Congress of Entomology. Daegu, Korea.

Tran, J., H.-W. Park and B. A. Federici. 2012. Regulatory genes affect insecticidal protein synthesis in Bacillus thuringiensis. Research in Science and Engineering Summer Research Symposium, University of California, Riverside. Riverside, California.

Pino, B. C., S. Kozervanich-Chong, E. A. Hafkenscheid, R. M. Oliverio, D. K. Bideshi and H.-W. Park. 2013. Cyt1Aa from Bacillus thuringiensis subsp. israelensis enhances mosquitocidal activity of B. thuringiensis subsp. kurstaki HD-1 against Aedes aegypti but not Culex quinquefasciatus. 38th Annual West Coast Biological Sciences Undergraduate Research Conference. San Diego, California.

Oliverio, R. M. and H.-W. Park. 2013. Partial characterization of the 144-kDa protein synthesized by Bacillus thuringiensis subsp. morrisoni PG-14. 5th Annual Research Seminar, California Baptist University, Riverside, California.

Park, H.-W., R. H. Hice and B. A. Federici. 2013. Molecular genetic basis for engineering small to large crystals of Cyt1Aa. 46th Annual Meeting of the Society for Invertebrate Pathology and Conference on Invertebrate Pathology and Microbial Control. Pittsburgh, Pennsylvania.

Sakano, Y., H.-W. Park, B. Ge, D. K. Bideshi and B. A. Federici. 2013. Characterization of a third promoter of the cyt1Aa gene of Bacillus thuringiensis subsp. israelensis. 46th Annual Meeting of the Society for Invertebrate Pathology and Conference on Invertebrate Pathology and Microbial Control. Pittsburgh, Pennsylvania.

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Church Membership & Activities

Magnolia Church, Riverside, California

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Personal Philosophy

But he was pierced for our transgressions, he was crushed for our iniquities; the punishment that brought us peace was upon him, and by his wounds we are healed. Isaiah 53:5

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